The alarming surge in chronic kidney disease among women

Tripling of Chronic Kidney Disease Cases in Women Raises Alarms Globally, Concept art for illustrative purpose - Monok

In a groundbreaking study, researchers at the Gujarat Adani Institute of Medical Sciences (GAIMS) unveiled startling findings on the surge of chronic kidney disease (CKD) among women worldwide.

Chronic kidney disease, an often-silent condition, has emerged as a critical global health concern, disproportionately impacting women over the last three decades. The study, presented at ASN Kidney Week 2024, draws attention to the complex interplay of factors fueling this rise, including the global increase in type 2 diabetes and hypertension cases among women, both known to be significant contributors to kidney disease.

CKD is currently recognized as one of the leading causes of illness and death worldwide. With its steady rise in prevalence and mortality rates, the disease now poses a serious health risk, particularly in resource-constrained regions where access to timely medical intervention is limited.

The GAIMS study analyzed global data spanning over 3 decades to understand the nuances of CKD’s prevalence among women, aiming to equip public health officials with the insights needed to address this mounting issue.

Key Takeaways

A recent study reveals a significant surge in chronic kidney disease (CKD) among women globally, with alarming rates of increase in prevalence and mortality.

  • Chronic kidney disease is currently recognized as one of the leading causes of illness and death worldwide, with a steady rise in prevalence and mortality rates.
  • The GAIMS study found that CKD cases among women have risen across diverse geographical landscapes, from Latin America to North America and other continents, with an annual 2.10% increase in CKD cases.
  • Preventive measures targeting high-risk women, such as lifestyle interventions, regular screenings, and health education, could significantly reduce CKD cases, while public awareness campaigns can help educate high-risk groups about CKD’s warning signs, risk factors, and management strategies.

CKD on the rise in women worldwide

Utilizing the Global Burden of Disease (GBD) report from 2021, the GAIMS study tracked the incidence and impact of CKD in women from 1990 to 2021, unveiling an annual 2.10% increase in CKD cases.

The study’s analysis indicated that this growth is not confined to any single region; instead, CKD cases among women have risen across diverse geographical landscapes, from Latin America to North America and across other continents. According to senior researcher Hardik Dineshbhai Desai, these findings represent a critical warning, underscoring the need for immediate intervention.

Moreover, the study highlighted that CKD-related deaths among women have climbed by an average of 3.39% per year, reflecting a clear trend of increasing severity. These figures demonstrate the global spread of CKD, marking it as an escalating health crisis and a significant concern for women’s health worldwide.

Not to mention the rise in disability-adjusted life years (DALYs) by 2.48% annually showcases the debilitating nature of CKD, impacting the quality of life and functional capacity for millions of affected women.

Beyond mere numbers, the implications of this trend are significant. CKD often progresses silently, with patients experiencing few symptoms until the condition reaches an advanced stage, making early diagnosis and intervention crucial.

Women, in particular, are more likely to experience undiagnosed or delayed treatment for CKD, which exacerbates the disease’s impact. The study argues that a proactive, multidisciplinary approach is essential to prevent CKD from further straining healthcare resources and disproportionately affecting female populations.

Disparities in CKD outcomes

The GAIMS study’s examination of regional data offers insight into how social determinants of health, such as access to healthcare and socioeconomic status, shape CKD outcomes. Latin America and North America, for instance, showed significant increases in CKD prevalence, with high annual growth rates in women.

These rates reflect the higher disease burden on women in these areas, where health inequities and lack of specialized care facilities can limit the effectiveness of early intervention and treatment.

In many lower-income and rural regions, healthcare infrastructures are often insufficient to manage chronic conditions like CKD. These areas face a severe shortage of nephrologists, inadequate screening facilities, and limited access to life-saving dialysis or transplant services, further intensifying CKD’s impact on women.

The study reveals that CKD outcomes are markedly worse in communities where preventive care, diagnostic tools, and ongoing management resources are scarce, highlighting the need for region-specific policies to improve outcomes.

Additionally, the study underscores that the lack of healthcare resources in these regions exacerbates the problem, causing undiagnosed or untreated CKD cases to advance rapidly. Desai and his team call for targeted healthcare investments that could bridge these disparities, allowing for more equitable access to diagnostic tools and treatment options.

Addressing CKD requires acknowledging these gaps and implementing health policies that reach underserved populations. The study advocates for investment in both preventive healthcare and public awareness campaigns to educate high-risk groups, especially women, about CKD’s warning signs, risk factors, and management strategies.

Prevention and early intervention

As a leading cause of kidney failure, CKD often leads to life-threatening complications if not caught early, and both prevention and early intervention play a crucial role in managing CKD. The GAIMS study emphasizes that preventive measures targeting high-risk women could significantly reduce CKD cases.

Desai points out that a holistic approach combining lifestyle interventions, regular screenings, and health education is vital to slowing CKD progression.

The study identifies hypertension and type 2 diabetes as major risk factors that are both preventable and manageable with appropriate healthcare resources. Public health officials are urged to adopt programs that address these conditions in tandem with CKD, recognizing the interconnected nature of chronic diseases.

For instance, community-based initiatives focused on healthier diets, exercise, and routine health check-ups can not only lower diabetes and hypertension rates but also prevent CKD.

Moreover, the researchers call for CKD-specific screening programs, particularly in high-risk regions, to ensure timely diagnosis and management.

The study’s authors advocate for greater public awareness about CKD’s risks and symptoms, recommending that healthcare providers prioritize routine kidney function tests for women, especially those with diabetes or high blood pressure. Early identification of CKD allows for intervention that can slow disease progression, reducing the likelihood of kidney failure and the need for dialysis or transplants.

CTA for all healthcare providers

The GAIMS study urges immediate action from policymakers, healthcare providers, and individuals worldwide to address the growing CKD crisis. Given CKD’s complex relationship with other chronic diseases, Desai advocates for integrated healthcare strategies that can address multiple conditions simultaneously.

He highlights the need for an inclusive approach that involves stakeholders from various sectors, including healthcare providers, community leaders, and researchers, to combat CKD’s spread effectively.

Desai emphasizes the role of governments in supporting CKD prevention and treatment efforts through policies that make healthcare accessible and affordable. He urges policymakers to prioritize investments in healthcare infrastructure and to create collaborations with healthcare organizations. Such efforts could ensure that even marginalized communities have access to essential diagnostic and treatment services.

The researchers further suggest that CKD prevention and management should be tailored to the needs of specific regions. By designing programs that are responsive to local health needs, governments can more effectively reduce CKD-related mortality and disability rates. For example, investing in mobile health clinics or telemedicine in rural areas can bring essential CKD care to communities where traditional healthcare infrastructure may be lacking.

The study also underscores the importance of collaboration among healthcare providers, researchers, and public health officials to promote CKD awareness and address its risk factors.

Public health campaigns, particularly those aimed at educating women on the links between CKD, diabetes, and high blood pressure, could play a pivotal role in curbing CKD’s prevalence. Collaborative efforts are key, as they bring together diverse expertise to develop and implement strategies that can reduce CKD’s impact on global health.

A better future for CKD outcomes for women

The findings from GAIMS represent a crucial turning point in the global response to CKD, serving as a call to action for healthcare providers, governments, and individuals alike. The study’s comprehensive analysis highlights the growing burden of CKD among women and the disparities that exacerbate the disease’s impact.

Policymakers and healthcare leaders are urged to consider the study’s insights as they work to develop targeted prevention and treatment strategies that can alleviate CKD’s global impact.

As the world confronts CKD’s rise, there is a pressing need for a multifaceted approach that encompasses preventive care, timely diagnosis, and equitable access to treatment. By addressing these priorities, stakeholders can help reduce the burden of CKD on women worldwide, ultimately fostering a healthier and more resilient global community.

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